Phenylpropanoid amides from whole plants of Corydalis edulis / 中国中药杂志

Ten phenylpropanoid amides were isolated from the whole plants of Corydalis edulis Maxim. by various of column chromatographies including silica gel, Sephadex LH-20, and ODS. Their structures were identified on the basis of physicochemical properties, MS, NMR, and IR spectroscopic data. These compounds were identified as N-trans-sinapoyl-3-methoxytyramine-4'-O-β-glucoside(1), N-trans-sinapoyl-3-methoxytyramine(2), N-trans-sinapoyltyramine(3), N-trans-p-coumaroyltyramine(4), N-trans-sinapoyl-7-hydroxytyramine(5), N-cis-feruloyltyramine(6), N-cis-p-coumaroyltyramine(7), N-trans-feruloyltyramine(8), N-trans-feruloyl-3-methoxytyramine(9), and N-trans-feruloyl-7-hydroxytyramine(10). Compound 1 is a new compound. Compounds 2-7 are obtained from the plants of Papaveraceae for the first time, while compounds 8-10 are firstly isolated from C. edulis.

Chemical constituents from whole herbs of Corydalis edulis / 中草药

Objective: To investigate the chemical constituents from the herbs of Corydalis edulis. Methods: The compounds were isolated and purified by various column chromatographies, and their structures were identified by physiochemical properties and spectroscopic data. Results: Fifteen compounds were isolated from the n-BuOH layer of EtOH extract of the herbs of C. edulis. and identified as 6, 7-methylenedioxydihydroisocoumarin (1), oxohydrastinine (2), 6, 7-dimethoyisoquinolin-1 (2H)-one (3), 6, 7-methylenedioxy-1 (2H)-isoquinolinone (4), (+)-syringaresinol (5), (+)-medioresinol (6), salidroside (7), isosalicin (8), icariside D2 (9), salicin (10), icariside F2 (11), icariside B2 (12), nicotinamide (13), pyrocatechol (14), and 5-hydroxyl-2-hydroxymethylpyridine (15), respectively. Conclusion: Compound 1 is a new natural product. Compounds 3, 5-12, 14, and 15 were isolated from Corydalis species for the first time. Compounds 2, 4, and 13 were firstly obtained from C. edulis.